Patient Recruitment Services and Patient Retention Services Market, Industry Analysis, and Forecast to 2035

Clinical trials are a fundamental requirement for evaluating the safety and efficacy of novel therapeutic interventions.

Initiating a clinical trial is a complex and time-consuming process, involving suitable planning and execution. In addition, there are several other challenges, including inefficiencies related to data handling, and difficulties associated with patient enrollment and retainment, which further complicates the process. It is worth mentioning that around 80% of the clinical trials are delayed due to insufficient patient recruitment. Further, 15% to 40% of the enrolled patients drop out before the studies are completed, significantly impacting product approvals / launch timelines.

Patient Recruitment Process
Recruitment of patients for clinical studies can be tedious and challenging, often requiring a lot of time and money. Therefore, a comprehensive plan is necessary for the successful enrollment of study participants in a clinical trial.

Factors Influencing Participation In Clinical Trials
There are various factors that influence the willingness of an individual to participate in clinical research.

Patient Outreach Methods and Retention Strategies
In order to meet the enrollment goals, sponsors, clinical research organizations and patient recruitment firms adopt a diverse range of patient outreach and recruitment strategies. Traditional media (newspapers, radio and television) is a widely used tool for targeting local audience and encouraging them to participate in clinical trials. However, there are certain emerging techniques, including electronic medical records, mobile applications, patient advocacy groups and social media that are revolutionizing the patient recruitment domain and are expected to reduce the timelines as well as cost of the clinical trials significantly.

In addition to patient enrollment, retention of the patients in the clinical trials is equally important for the success of the research study. Presently, a number of players offer different patient retention services, such as study-branded gifts and reminders, education and support materials, reimbursement programs, transportation programs, patient engagement websites, patient reconnect programs and mobile applications.

Outsourcing of Patient Recruitment
One of the biggest challenges in patient recruitment services and patient retention services market is that some trials are too large or geographically broad to be managed by internal staff. It is worth mentioning that only 15% of the drug manufacturers have dedicated patient recruitment groups in place. In addition, the patient enrollment process in clinical studies is governed by various ethical and regulatory standards. As a result, sponsors are outsourcing almost all the non-core activities while retaining in-house research and development. Using the services of patient recruitment firms, a drug developer can expedite the enrollment of individuals in trials. Further, these firms have specific teams to develop promotional strategies for better patient enrollment.

Concluding Remarks
The availability of various digital data generation and management platforms has contributed significantly to the advancement of patient recruitment and retention domain. However, very few companies have the required expertise and resources to carry out effective patient enrolment and engagement in the clinical studies. In addition, clinical trials evaluating orphan drugs and personalized therapies require a specialized pool of eligible patients, having a specific and potentially rare, genetic / phenotypic / indication-related profile, which is a major challenge for drug developers. As a result, outsourcing the patient recruitment operations to contract service providers has gained popularity as an operational model.

For more information, please click on the following link:
https://www.rootsanalysis.com/....blog/patient-recruit

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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

Smart pharmaceutical and healthcare labels: Lets trace medicines from its origin

Traditionally, text and images were printed on pharmaceutical products to convey important information.

In recent years, the use of smart labels allows the developer to convey a greater amount of information about the product to the consumers, without the need for additional packaging space. It is worth noting that smart labels contain a transponder code which can be read by sophisticated devices, including radio frequency identification device (RFID) tags and near-field communication (NFC) chips. While most smartphones can read NFC chips, RFID tags can only be read by specialized receivers. Further, smart labels play a critical role in the manufacturing of pharmaceuticals. Some of the ways in which smart labels can aid the pharmaceutical production process include enhancing productivity and accuracy, managing inventory, and maintaining the quality of products.

Types of Smart Label
There are various types of smart labels which function in different frequency ranges and eases the workload of healthcare professionals and stakeholders in this domain.

Radio Frequency Identification Device (RFID)
RFID labels function in conjunction with an RFID reader, a data processing system, and a tag, with an embedded identification chip. The reader is an electronic system, with one or more antennas that transmit radio waves and read signals from RFID tags. In addition to the features of typical barcode labels, RFID labels offer numerous advantages. Since these labels use radio waves, scanning them does not require a clear line of sight. As a result, products are not required to be unpacked from their containers in order to be scanned and multiple products may be scanned at once, thereby, saving time.
Moreover, based on the frequency ranges employed to convey data, RFID tags may be classified into three categories: low frequency (LF), high frequency (HF) and ultra-high frequency (UHF). More details on the aforementioned categories have been discussed below:
 LF RFID systems have a scan range of up to 10 cm and operate in the 30 KHz to 300 KHz band. Although they operate better in the presence of metal or liquids, as compared to other technologies, they have a shorter read range and a slower data read rate (which may interfere with other types of RFID tag transmissions).
 HF RFID systems provide reading distances of 10 cm to 1 m and operate in the 3 MHz to 30 MHz frequency range. The applications of HF RFID include tracking surgical tools and secured access control.
 UHF RFID systems provide quicker data transfer rates, read ranges of up to 12 m, and operate in the frequency range between 300 MHz and 3 GHz. Although they are more susceptible to electromagnetic interference, metals, liquids and other impurities, recent design advancements have helped in alleviating some of these issues. Due to their lower manufacturing costs, UHF tags are more frequently used in applications such as pharmaceutical anti-counterfeiting, inventory tracking and patient tracking.

Near-Field Communication (NFC)
NFC is a type of RFID, which is a contactless technology used for communication, that operates in a frequency range centered on 13.56 MHz. This technology enables users to wirelessly transfer identity data to the recipient for security and tracking purposes. Further, NFC technology is utilized in a variety of fields, including manufacturing, medical, banking and finance sectors, due to its ability to be is used within a defined range and reasonably safe nature. NFC chips may be included into product tags, labels and marketing materials, providing customers with an easy approach to extend their brand experiences into the digital world. NFC labels are also used to point customers to websites where they can find out more about the product or the brand than can be put on a label.
These smart labels thus assist in preventing counterfeit pharmaceutical / medical products coming into the market.
For more information, please click on the following link:
https://www.rootsanalysis.com/....blog/smart-pharmaceu

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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

Introduction To Exosome Therapeutics

In recent years, therapies utilizing extracellular vesicles have garnered significant attention among the industry stakeholders for the treatment of diverse target indication, primarily owing to the various benefits offered by them, including target specificity, enhanced tissue regeneration, and reduced inflammation and chronic pain.

Over time, various research studies have demonstrated the potential of exosomes (membrane bound extracellular vesicles) in disease diagnosis, drug delivery and therapeutic applications. As a result, exosome therapeutics domain has been gaining traction recently.

INTRODUCTION TO EXOSOMES
Exosomes are extracellular vesicles, which have endosomal origin and may contain different biomolecules, including proteins, DNA, lipids, miRNA or RNA, based on the type of cell of their origin and its conditions.
Exosomes convey a wide range of information to the target cells, depending on their source. In addition, they are involved in regulating the expression of the targets that are linked to RNA as they can affect the expression of RNA.

TYPES OF EXTRACELLULAR VESICLES
Micro-vesicles have size of about 100 nm and are formed by direct outward budding of the plasma membrane. Their formation solely depends on the surrounding environment and this process requires the presence of cytoskeleton components, namely actin/
Exosomes have a diameter in the range between 30-150 nm and are formed by inward budding and get developed into the multivesicular bodies (MVBs). Owing to their long half-life, exosomes can target specific organs of the body, which makes them widely studied vesicles for immunological purposes.
Apoptotic bodies have a diameter of about 5,000 nm and formed after the separation of plasma membrane from the skeleton. They can be easily distinguished from micro vesicles and exosomes because of their unscathed organelles as well as chromatin.

EXOSOME BIOGENESIS, FORMATION, DEVELOPMENT AND SECRETION
Exosomes are known to arise from the inward folding of multi-vesicular bodies (MVBs) in order to form the intraluminal vesicles (ILVs).
These MVBs are then delivered to the trans-Golgi network (TGN) for the recovery of endosomes, which further move to lysosome for degeneration of the carried substances. The most essential component of exosome biogenesis is the formation of ESCRT.

Formation and development of exosomes:
 Sorting of internalized cargoes into early endosomes
 Maturation into late endosomes or multivesicular bodies
 Delivery of cargoes from trans-Golgi network and cytosol
 Exosomes cargo in multivesicular bodies are transported to plasma membrane
 Fusion with the plasma membrane
 Secretion of exosomes

ADVANTAGES AND FUTURE POTENTIAL OF EXOSOME THERAPEUTICS:
Advantages:
 High Compatibility: Exosomes are naturally occurring compounds that can withstand digestive enzymes.
 Low Immunogenicity: Due to the innate properties of exosomes including their potential tissue of cell selectivity.
 Targeted Drug Delivery: Ability to cross blood brain barrier cause lesser systemic effects and low toxicity.
Future Potential:
 Several emerging players have undertaken initiatives to explore the potential of exosomes for diagnosis of various diseases.
 Application of exosomes as biomarker or vector of various potential therapeutic molecules, represents a theragnostic approach.
 Advanced exosome technologies are being developed to fully substructure the potential therapeutic applications of exosomes.

For additional details, please visit https://www.rootsanalysis.com/....blog/introduction-to

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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

Unlocking the Potential of Digital Twins in Healthcare: Benefits, Challenges and Opportunities

The application of digital twins in healthcare has the potential to revolutionize patient care, improve clinical outcomes, and reduce costs.
Digital twins, or virtual replicas of physical objects and environments, are being used in many different industries, and healthcare is no exception. In healthcare, these can be used to provide better patient monitoring, improve remote care, and create personalized treatments. With the help of digital twins, healthcare providers can gain access to real-time data from patients and be better equipped to understand the physical, mental, and emotional needs of their patients. However, there are some challenges that need to be addressed before digital twins can be used to their full potential in healthcare. This article will explore the benefits, challenges and opportunities that come with using digital twins in this domain.

What is a Digital Twin?
Digital twins are virtual representations of real-world objects. A digital twin is a piece of equipment, for example, may have the same functionality as the physical counterpart. Digital twins can be created using a wide range of data sources, such as sensors, models, and images. In the context of healthcare, these technologies can include the full representation of a patient’s medical history, symptoms, current treatment, and even biometric data, such as blood pressure and heart rate.

Benefits Associated with The Use of Digital Twins
Digital twins offer many benefits to the healthcare industry. In the following sections, we explore the top three benefits offered by digital twin technologies.
• Real-Time Data Access – While physical objects can be monitored and controlled, the data is often delayed. A digital twin, on the other hand, can be almost immediately updated with data. This means that healthcare providers can see and respond to real-time changes / real world evidence and abnormalities.
• Improved Remote Care – Remote care is when healthcare is provided to patients who are not physically in a healthcare facility. Remote care is growing in popularity, but it comes with several challenges, such as a lack of real-time data and an inability to supervise the patient. Digital twins can help with these challenges by providing real-time data and allowing healthcare providers to view the patient remotely (telemedicine support).
• Personalized Treatment – Digital twins can be used to create personalized treatment plans for patients. Using data from physical objects, such as equipment and machinery, and biometric data, such as blood pressure and heart rate, digital twins can create a 3D model of the patient’s health.

Disadvantages Associated with The Use of Digital Twins
For all the benefits of digital twins, there are still some challenges that need to be addressed. In the following sections, we explore the top three challenges.
• Difficulty in Adoption – Digital twins have been in use since the early 2000s, but they have only recently started to be used in healthcare. This is largely due to the fact that digital twins have been primarily used in industrial settings and that the concept has been hard for healthcare providers to grasp. While many find the concept of a digital twin attractive, it has been challenging for healthcare providers to adopt the concept.
• Possibility of False Information – When data is fed into a digital twin, it can be inaccurate or incomplete. This can lead to incorrect findings and incorrect treatment plans. However, there are some efforts underway to solve this problem. One approach is to make the data used to create the digital twin as accurate as possible. Another approach is to let the digital twin correct itself based on new data.


Future Perspectives
In the following sections, we explore three ways in which the use of digital twins in healthcare can be improved.
• Better Adoption Rates – With better adoption rates, healthcare providers will be able to use digital twins to their full potential. With the help of vendors and organizations, such as the Industrial Internet Consortium, healthcare providers can be better informed about the advantages of digital twins.
• Improved Data Accuracy – One way to improve the use of digital twins in healthcare is to make sure that the data used to create the digital twin is as accurate as possible. By doing this, digital twins will be able to provide better personalized treatment plans and make better decisions about patient care.
• Better Data Visualization – While digital twins provide plenty of data, it’s hard for healthcare providers to understand and visualize that data. One way to solve this problem is to provide healthcare providers with visualizations that make it easy to understand the data.

Despite their immense rise in popularity, digital twins still have some issues that need to be resolved. As such, there are some ways in which the use of digital twins in healthcare can be improved.

For additional details, please visit https://www.rootsanalysis.com/....blog/digital-twins-i or email sales@rootsanalysis.com

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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

Investment Opportunities in Women’s Digital Health

Digital health is a broad term that refers to the utilization of communication and information technologies to manage, track, and improve the overall healthcare delivery system.

Owing to the potential of digital technology to optimize patient healthcare and the development of pharmaceuticals, the digital healthcare industry has witnessed significant rise in investments in the past decade, including in the women’s digital health space. It is worth noting that the digital health initiative is mainly focused on developing and providing a range of easy-to-use and innovative tools to patients, scientists / researchers, healthcare professionals, and other industry stakeholders for better health management. A significant increase in adoption of digital solutions has been witnessed in this field, especially after the outbreak of pandemic.
Over the years, several initiatives have been undertaken by various industry stakeholders across the globe to promote digital health solutions and their applications. For instance, in 2019, the Preventive Healthcare tool was launched by Facebook to connect people to different health resources, enabling its users to set reminders for checkups, schedule tests and track their past activity.

Women’s Digital Health
Women’s digital health or FemTech is a broad industry that offers various products, services, diagnostic tools, wearable devices, software, applications and technologies in order to address the issues associated with women’s health, including menstrual, reproductive, ****ual, maternity, and menopause disorders. Since it is primarily focused on women’s healthcare, it has been termed as Female Technology or FemTech.
In the past few years, several investments have been made by various institutional investors in the companies associated with women’s digital health sector. For instance, in April 2022, USD 28.5 million was raised by Evernow in venture series A for re-defining the menopause treatment. Additionally, in February 2022, USD 15 million was raised by Ro in venture series E to expand its direct-to-patient healthcare model.

Key Application Areas of FemTech Industry
The FemTech industry provides an opportunity for better self-management, enabling and empowering women to be more in control of their own health and wellbeing.

Future Perspectives
Owing to the increased adoption rate of digital solutions and rise in the demand for telehealth services, the companies involved in the women’s digital health domain have witnessed a surge in the investment activity. Subsequently, capital investments worth more than USD 3 billion have been made in this domain, over the past few years. Nearly 90% of the capital invested in the companies has, so far, come in from venture capital funding; some companies have already gone public. Moreover, there is a high unmet need in certain areas, such as management of mental health, disease conditions, such as PCOS, endometriosis and disease which have high prevalence among women. In order to identify the gaps and unmet needs, it is important to develop customized and focused solutions, and establish policies that can help in increasing awareness about women’s health. Given the potential of digital health solutions, with the development of affordable and accessible digital technologies, the healthcare service industry is expected to witness noteworthy growth in the coming years. Furthermore, taking into consideration the ongoing efforts to develop solutions for existing unmet needs, we expect the women’s digital health market to present numerous lucrative investment opportunities in the future.
For additional details, please visit https://www.rootsanalysis.com/....blog/womens-digital-

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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com